个人简介

2017年6月毕业于中国药科大学药物科学研究院，获药物代谢动力学博士学位，同年7月入职南京市儿童医院重点实验室，2019年1月评为助理研究员。现任《南京医科大学学报（自然科学版）》第一届青年编委、Scientific Report及Plos One期刊审稿人。

主持科研项目

1.NEK7在急性肾小管损伤中的作用及机制研究（81800599），国家自然科学基金青年项目，2019/01-2021/12，21 万元

2.Twist-2/MicroRNA-214轴在原发性高血压中的作用及机制研究（ZKX18039），南京市医学科技发展重点项目，2019/01-2021/12，20 万元

3.线粒体呼吸链活性调控在糖尿病肾病中的作用研究（KF-2018-05），肾脏疾病国家重点实验室开放课题，2018/12-2020/12，5 万元

4.NIMA相关激酶7/端粒蛋白复合体途径在急性肾小管损伤中的作用（BK20180145），江苏省自然科学基金青年基金项目，2018/07-2021/06，20万元 

5.NEK7在顺铂引起的急性肾小管损伤中的保护作用及机制（2018M632342），中国博士后科学基金第63批面上资助，2018/06-2020/06，5万元

代表性论文

1.Mengqiu Wu#, Hui Ye#, Zhiyuan Tang#, Chang Shao, Gaoyuan Lu, Baoqiang Chen, Yuyu Yang, Guangji Wang*, Haiping Hao*, p53 dynamics orchestrates with binding affinity to target genes for cell fate decision, Cell Death & Disease. 2017, 8(10): e3130.

2.Mengqiu Wu, Weiyi Chen, Shengnan Zhang, Songming Huang, Aihua Zhang, Yue Zhang*, Zhanjun Jia*, Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus, Apoptosis. 2019, 24:879-891.

3.Mengqiu Wu#, Hui Ye#, Chang Shao, Xiao Zheng, Qingran Li, Lin Wang, Min Zhao, Gaoyuan Lu, Baoqiang Chen, Jun Zhang, Yun Wang, Guangji Wang*, Haiping Hao*, Metabolomics-proteomics combined approach identifies differential metabolism-associated molecular events between senescence and apoptosis, Journal of Proteome Research. 2017, 16(6):2250-2261.  

4.Mengqiu Wu, Shuzhen Li, Xiaowen Yu, Weiyi Chen, Haoyang Ma, Chang Shao, Yue Zhang, Aihua Zhang, Songming Huang*, Zhanjun Jia*, Mitochondrial activity contributes to impaired renal metabolic homeostasis and renal pathology in STZ-induced diabetic mice, American Journal of Physiology-Renal Physiology.2019,317:F593-F605.

5.Mengqiu Wu, Weiyi Chen, Xiaowen Yu, Dan Ding, Wen Zhang, Hu Hua, Man Xu, Xia Meng, Xuejuan Zhang, Yue Zhang, Aihua Zhang, Zhanjun Jia*, Songming Huang*, Celastrol aggravates LPS-induced inflammation and injuries of liver and kidney in mice, American Journal of Translational Research. 2018,10 (7): 2078-2086. 

6.Zhiyuan Tang, Mengqiu Wu, Yingchun Li, Xiao Zheng, Huiying Liu, Xuefang Cheng, Xu Lin, Guangji Wang*, Haiping Hao*, Absolute quantification of NAD(P)H: quinone oxidoreductase 1 in human tumor cell lines and tissues by liquid chromatography-mass spectrometry/mass spectrometry using both isotopic and non-isotopic internal standards, Analytica Chimica Acta. 2013,772:59-67.

7.Hu Hua#, Xuhua Ge#, Mengqiu Wu, Chunhua Zhu, Lihong Chen, Guangrui Yang, Yue Zhang, Songming Huang, Aihua Zhang*, Zhanjun Jia*, Rotenone protects against acetaminophen-induced kidney injury by attenuating oxidative stress and inflammation, Kidney Blood Pressure Research. 2018,43(4):1297-1309.

8.Chang Shao, Wenjie Lu, Ning Wan, Mengqiu Wu, Qiuyu Bao, Yang Tian, Gaoyuan Lu, Nian Wang, Haiping Hao*, Hui Ye*, Integrative omics analysis revealed that metabolic intervention combined with metronomic chemotherapy selectively kills cancer cells. Journal of Proteome Research. 2019,18(6):2643-2653.

9.Lin Wang#, Hui Ye#, Di Sun, Tuo Meng, Lijuan Cao, Mengqiu Wu, Min Zhao, Yun Wang, Baoqiang Chen, Xiaowei Xu, Guangji Wang*, Haiping Hao*, Metabolic pathway extension approach for metabolomic biomarker identification. Analytical Chemistry. 2017,89(2):1229-1237.

授权专利

1.发明专利：鱼藤酮在胰岛保护中的应用，专利号：ZL201810725780.4，发明人：贾占军，吴梦秋，张爱华，张玥，麻昊阳，陈维宜；中国专利，授权日：2019年4月12日